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TYVASO and TYVASO DPI are approved for the treatment of pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3) to improve the ability to exercise.

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TYVASO NEBULIZER

Fits into your day

This portable nebulizer allows for dosing at home or on the go.

A simple way to remember: count to 4 and add 1 more

Set up device 1x each morning

Each session takes about 2-3 minutes

Take TYVASO 4x daily during waking hours

Clean device 1x each night

"...I adapted to using TYVASO very quickly and easily.
It's just become part of my normal routine"

— Catherine, living with PH-ILD and taking TYVASO

Hear Catherine's Story

Work with your doctor to reach your optimal dose from the TYVASO nebulizer

Your doctor will work with you to increase the number of breaths per session each week until you reach your optimal dose. It took patients in the clinical study an average of 3 weeks to reach their optimal dose.

Plan to take your medication 4x daily, approximately every 4 waking hours.

  • One ampule of TYVASO contains enough medicine for all 4 treatment sessions in a day

  • Each treatment session takes about 2 to 3 minutes

  • Most patients start with 3 breaths per treatment, 4x daily, and increase the number of breaths per session each week until they reach their optimal dose

There’s no set maximum dose of TYVASO. Your doctor will adjust your dose to find the amount that works best for you. 

Why is it important to reach your optimal dose? Your optimal dose will help you get the full benefit of your medicine. Through the titration process, you’ll take your prescribed dose 4x daily as directed by your doctor.

Reaching your optimal dose to maximize benefits

It is important to reach your optimal dose so that you can get the full benefit of the medicine and be more active.

At week 16 in the clinical study, patients achieving 10-12 breaths with the TYVASO nebulizer had a 67% greater improvement in their 6-minute walk test (6MWT) distance than those only achieving 7-9 breaths.

*59 feet is about 18 meters. 98 feet is about 30 meters.

What to expect when titrating

  • As you increase your dose each week, you may experience side effects
  • Talk to your nurse or doctor to help you manage side effects so that you can reach your optimal dose and experience the full benefits of TYVASO
  • DO NOT STOP taking TYVASO without talking to your healthcare provider

The titration process: Tina’s story

Listen to Tina share her experience titrating with TYVASO in order to reach her target maintenance dose.

Watch how to use the TYVASO Nebulizer

TYVASO is delivered through a portable nebulizer.

See the patient brochure for more information.

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TYVASO Quick Tips Guide

Download the TYVASO Nebulizer Quick Tips Guide for helpful tips on setting up, operating, transporting, and cleaning your device.

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TYVASO Instructions For Use Manual

Download the full Instructions for Use manual for the complete, detailed instructions on operating your device.

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Find out about TYVASO DPI

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Learn more about cost assistance

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IMPORTANT SAFETY
INFORMATION

Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have or have had bleeding problems
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IMPORTANT SAFETY
INFORMATION

COLLAPSE

Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have or have had bleeding problems
  • Have asthma or chronic obstructive pulmonary disease (COPD)
  • Are pregnant or plan to become pregnant. It is not known if either product will harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if either product passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Either product and other medicines may affect each other.

Especially tell your healthcare provider if you take:

  • Medicines used to treat high blood pressure or heart disease
  • Medicines that decrease blood clotting (anticoagulants)
  • Water pills (diuretics)
  • Gemfibrozil (Lopid®) or rifampin (Rimactane®, Rifadin®, Rifamate®, Rifater®)

What are the possible side effects of TYVASO or TYVASO DPI?

Both products can cause serious side effects, including:

  • Low blood pressure (symptomatic hypotension). If you have low blood pressure, either product may lower your blood pressure more.
  • Bleeding problems. Either product may increase the risk of bleeding, especially in people who take blood thinners (anticoagulants).

The most common side effects of both products are cough, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), fainting or loss of consciousness, dizziness, diarrhea, and shortness of breath. Like other inhaled prostaglandins, you may have trouble breathing after taking TYVASO or TYVASO DPI because it may cause the muscles around your airway to tighten (bronchospasm). These are not all the possible side effects. Call your doctor for medical advice about side effects or if you have trouble breathing.

You may report side effects to the FDA at 

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or call 1-800-FDA-1088.

What are TYVASO and TYVASO DPI?

TYVASO (treprostinil) Inhalation Solution and TYVASO DPI (treprostinil) Inhalation Powder are prescription medicines used in adults to treat:

  • Pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. TYVASO or TYVASO DPI can improve the ability to exercise. Your ability to exercise decreases 4 hours after taking TYVASO or TYVASO DPI. It is not known if TYVASO or TYVASO DPI is safe and effective in children under 18 years of age.
  • Pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3), which is high blood pressure in the lungs due to inflammation and sometimes scarring in the lungs. TYVASO or TYVASO DPI can improve the ability to exercise.

The risk information provided here is not comprehensive. To learn more about TYVASO or TYVASO DPI, talk with your healthcare provider. Please see Full Prescribing Information for TYVASO or TYVASO DPI, Instructions for Use manuals for TD-100 and TD-300 TYVASO® Inhalation System and TYVASO DPI® Inhalation Powder, and additional information at www.TYVASO.com or call 1-844-UNITHER (1-844-864-8437).


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DPI=dry powder inhaler.