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TYVASO and TYVASO DPI are approved for the treatment of pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3) to improve the ability to exercise.

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TYVASO DPI

Fits in the palm of your hand

TYVASO is available in a Dry Powder Inhaler (DPI).

This small, portable inhaler uses cartridges and features a simple-to-use design.

Single-dose
cartridges prefilled
with medicine

Just 1 breath per
cartridge, 4x daily

No cleaning
required

Taking a dose is as simple as:
JUST ONE BREATH—
OPEN, LOAD, INHALE

patient satisfaction rate with TYVASO DPI

TYVASO DPI received high satisfaction marks from 45 of 46 people who switched from the TYVASO nebulizer in a clinical study.*

*In the clinical study, 51 people with PAH who had been using the TYVASO nebulizer for at least 3 months switched to TYVASO DPI. Researchers recorded side effects, and after 3 weeks, 46 patients rated their satisfaction with TYVASO DPI in a questionnaire.

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"I would definitely suggest talking to your doctor about TYVASO DPI"

— Sally, living with PH-ILD and taking TYVASO DPI

Hear Sally's Story

Work with your doctor to reach your optimal dose of TYVASO DPI

Your doctor will work with you to increase your dose until you reach your optimal dose. This process is called "titration."

Plan to take your medication 4x daily, approximately every 4 waking hours.

  • Doses are taken in 1 breath per cartridge

  • Most people start with the 16 mcg cartridge, 4x daily, and increase their dose every 1-2 weeks until they reach their optimal dose

There's no set maximum dose of TYVASO DPI. If your prescribed dose is higher than 64 mcg, you may need 2 cartridges. Your doctor will adjust your dose to find the amount that works best for you.

Why is it important to reach your optimal dose? Your optimal dose will help you get the full benefit of your medicine. Through the titration process, you’ll take your prescribed dose 4x daily as directed by your doctor.

Multiple-cartridge dosing

Depending on your prescribed dose, you may need 2 cartridges. For example, if prescribed 80 mcg, you may use:

What to expect when titrating

  • As you increase your dose each week, you may experience side effects
  • Talk to your nurse or doctor to help you manage side effects so that you can reach your optimal dose and experience the full benefits of TYVASO DPI
  • DO NOT STOP taking TYVASO DPI without talking to your healthcare provider

See the patient brochure for more information.



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Watch how simple it is to use TYVASO DPI

TYVASO DPI

Download the full TYVASO DPI Instructions for Use manual for additional information.

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TYVASO DPI Titration Guide

Download the TYVASO DPI Titration Guide for more information on how to reach your target dose.

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Hear from other patients who choose TYVASO DPI.

PATIENT STORIES

IMPORTANT SAFETY
INFORMATION

Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have or have had bleeding problems
EXPAND

IMPORTANT SAFETY
INFORMATION

COLLAPSE

Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have or have had bleeding problems
  • Have asthma or chronic obstructive pulmonary disease (COPD)
  • Are pregnant or plan to become pregnant. It is not known if either product will harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if either product passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Either product and other medicines may affect each other.

Especially tell your healthcare provider if you take:

  • Medicines used to treat high blood pressure or heart disease
  • Medicines that decrease blood clotting (anticoagulants)
  • Water pills (diuretics)
  • Gemfibrozil (Lopid®) or rifampin (Rimactane®, Rifadin®, Rifamate®, Rifater®)

What are the possible side effects of TYVASO or TYVASO DPI?

Both products can cause serious side effects, including:

  • Low blood pressure (symptomatic hypotension). If you have low blood pressure, either product may lower your blood pressure more.
  • Bleeding problems. Either product may increase the risk of bleeding, especially in people who take blood thinners (anticoagulants).

The most common side effects of both products are cough, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), fainting or loss of consciousness, dizziness, diarrhea, and shortness of breath. Like other inhaled prostaglandins, you may have trouble breathing after taking TYVASO or TYVASO DPI because it may cause the muscles around your airway to tighten (bronchospasm). These are not all the possible side effects. Call your doctor for medical advice about side effects or if you have trouble breathing.

You may report side effects to the FDA at 

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or call 1-800-FDA-1088.

What are TYVASO and TYVASO DPI?

TYVASO (treprostinil) Inhalation Solution and TYVASO DPI (treprostinil) Inhalation Powder are prescription medicines used in adults to treat:

  • Pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. TYVASO or TYVASO DPI can improve the ability to exercise. Your ability to exercise decreases 4 hours after taking TYVASO or TYVASO DPI. It is not known if TYVASO or TYVASO DPI is safe and effective in children under 18 years of age.
  • Pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3), which is high blood pressure in the lungs due to inflammation and sometimes scarring in the lungs. TYVASO or TYVASO DPI can improve the ability to exercise.

The risk information provided here is not comprehensive. To learn more about TYVASO or TYVASO DPI, talk with your healthcare provider. Please see Full Prescribing Information for TYVASO or TYVASO DPI, Instructions for Use manuals for TD-100 and TD-300 TYVASO® Inhalation System and TYVASO DPI® Inhalation Powder, and additional information at www.TYVASO.com or call 1-844-UNITHER (1-844-864-8437).


TYVISIconSEP2024

DPI=dry powder inhaler; PAH=pulmonary arterial hypertension.