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TYVASO and TYVASO DPI are approved for the treatment of pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3) to improve the ability to exercise.

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How to Take TYVASO

TYVASO is a medication you inhale directly to your lungs. TYVASO is inhaled during 4 short treatment sessions each day.

TYVASO DPI

TYVASO DPI (treprostinil) Inhalation Powder

TYVASO Nebulizer

TYVASO (treprostinil) Inhalation Solution

Portability

Small, portable dry powder inhaler that fits in the palm of your hand

Handheld nebulizer that is rechargeable for cordless flexibility

Setup

Insert single-dose cartridge and take a breath. Replace inhaler every 7 days. No refrigeration is required for TYVASO DPI inhaler or cartridges

Set up device 1x each morning, clean device 1x each night

Dosing

4x daily
Each dose is inhaled in less than 2 seconds

4x daily
Each session takes about 2-3 minutes

Titration

Most people start with a 16 mcg cartridge and take 1 breath per cartridge, 4x daily. The dose is then typically increased to the next cartridge strength every 1-2 weeks* until they reach their optimal dose

Learn more about TYVASO DPI and how to reach your optimal dose.

GO TO TYVASO DPI

Most people start with 3 breaths, 4x daily, and increase by 3 breaths per session every week to reach their optimal dose

Learn more about the TYVASO nebulizer and how to reach your optimal dose.

GO TO TYVASO NEBULIZER
TYVASO DPI

TYVASO DPI (treprostinil) Inhalation Powder

Portability

Small, portable dry powder inhaler that fits in the palm of your hand

Setup

Insert single-dose cartridge and take a breath. Replace inhaler every 7 days. No refrigeration is required for TYVASO DPI inhaler or cartridges

Dosing

4x daily
Each dose is inhaled in less than 2 seconds

Titration

Most people start with a 16 mcg cartridge and take 1 breath per cartridge, 4x daily. The dose is then typically increased to the next cartridge strength every 1-2 weeks* until they reach their optimal dose

Learn more about TYVASO DPI and how to reach your optimal dose.

GO TO TYVASO DPI
TYVASO Nebulizer

TYVASO (treprostinil) Inhalation Solution

Portability

Handheld nebulizer that can be charged overnight for cordless flexibility

Setup

Set up device 1x each morning, clean device 1x each night

Dosing

4x daily
Each session takes about 2-3 minutes

Titration

Most people start with 3 breaths, 4x daily, and increase by 3 breaths per session every week to reach their optimal dose

Learn more about the TYVASO nebulizer and how to reach your optimal dose.

GO TO TYVASO NEBULIZER

You and your doctor will work together to find your optimal dose, ensuring you get the maximum benefits from your treatment. Titrating to your optimal dose is important for achieving better outcomes. Titration schedules may vary based on how you tolerate the medicine.

*If the prescribed dose is higher than 80 mcg per treatment session, more than 1 cartridge will be needed per session.

TYVASO device options: TYVASO DPI and TYVASO Nebulizer

Learn more about the device options, TYVASO DPI and the TYVASO nebulizer, and which option may be right for you.

“Fortunately, I was able to move up smoothly each week to get to my maintenance dose.*”

— Sally, living with PH-ILD and taking TYVASO DPI
HEAR SALLY’S STORY

*Individual results may vary.

Learn more about managing your side effects.

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IMPORTANT SAFETY
INFORMATION

Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have or have had bleeding problems
EXPAND

IMPORTANT SAFETY
INFORMATION

COLLAPSE

Before you take TYVASO or TYVASO DPI, tell your healthcare provider about all of your medical conditions, including if you:

  • Have low blood pressure
  • Have or have had bleeding problems
  • Have asthma or chronic obstructive pulmonary disease (COPD)
  • Are pregnant or plan to become pregnant. It is not known if either product will harm your unborn baby.
  • Are breastfeeding or plan to breastfeed. It is not known if either product passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Either product and other medicines may affect each other.

Especially tell your healthcare provider if you take:

  • Medicines used to treat high blood pressure or heart disease
  • Medicines that decrease blood clotting (anticoagulants)
  • Water pills (diuretics)
  • Gemfibrozil (Lopid®) or rifampin (Rimactane®, Rifadin®, Rifamate®, Rifater®)

What are the possible side effects of TYVASO or TYVASO DPI?

Both products can cause serious side effects, including:

  • Low blood pressure (symptomatic hypotension). If you have low blood pressure, either product may lower your blood pressure more.
  • Bleeding problems. Either product may increase the risk of bleeding, especially in people who take blood thinners (anticoagulants).

The most common side effects of both products are cough, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), fainting or loss of consciousness, dizziness, diarrhea, and shortness of breath. Like other inhaled prostaglandins, you may have trouble breathing after taking TYVASO or TYVASO DPI because it may cause the muscles around your airway to tighten (bronchospasm). These are not all the possible side effects. Call your doctor for medical advice about side effects or if you have trouble breathing.

You may report side effects to the FDA at 

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or call 1-800-FDA-1088.

What are TYVASO and TYVASO DPI?

TYVASO (treprostinil) Inhalation Solution and TYVASO DPI (treprostinil) Inhalation Powder are prescription medicines used in adults to treat:

  • Pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. TYVASO or TYVASO DPI can improve the ability to exercise. Your ability to exercise decreases 4 hours after taking TYVASO or TYVASO DPI. It is not known if TYVASO or TYVASO DPI is safe and effective in children under 18 years of age.
  • Pulmonary hypertension associated with interstitial lung disease (PH-ILD; WHO Group 3), which is high blood pressure in the lungs due to inflammation and sometimes scarring in the lungs. TYVASO or TYVASO DPI can improve the ability to exercise.

The risk information provided here is not comprehensive. To learn more about TYVASO or TYVASO DPI, talk with your healthcare provider. Please see Full Prescribing Information for TYVASO or TYVASO DPI, Instructions for Use manuals for TD-100 and TD-300 TYVASO® Inhalation System and TYVASO DPI® Inhalation Powder, and additional information at www.TYVASO.com or call 1-844-UNITHER (1-844-864-8437).


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DPI=dry powder inhaler.