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Full Prescribing
Information

  • Home
  • About TYVASO
  • Starting TYVASO
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    UNDERSTANDING
    PAH

    What is PAH?

    People with pulmonary arterial hypertension (PAH) have an imbalance of 1 or more of 3 natural substances, causing the blood vessels in their lungs to become narrowed. When these 3 substances are out of balance, it is harder to keep blood flowing through the lungs and this causes symptoms of PAH, such as shortness of breath and fatigue when doing activities.

    There are medicines that address each of those 3 imbalances, or pathways, associated with PAH. Each PAH medicine targets only one of those pathways.

    Portrait of smiling woman on picnic with her kidsPortrait of smiling woman on picnic with her kids
    Side by side: healthy vessel, vessel with PAH.Side by side: healthy vessel, vessel with PAH.

    What is Prostacyclin? [pra·stuh·si·klin]

    Prostacyclin is one of the pathways associated with PAH. Prostacyclin helps ensure blood vessels are healthy and stay open. People who have PAH may not produce enough prostacyclin in their lungs.

    TYVASO Helps to Replace the Natural Prostacyclin You May Be Missing

    TYVASO mimics some of the effects of natural prostacyclin, helping to open up blood vessels and keep the blood flowing through your lungs.

    Portrait of man at grocery shopping and talking on cell phone.Portrait of man at grocery shopping and talking on cell phone.

    How Can TYVASO Help Me?

    TYVASO may help you do more in your day and do what matters most.

    SEE TYVASO BENEFITS

    You May Have Side Effects

    Talk to your healthcare provider and click below to learn more about potential side effects.

    WHAT SHOULD I KNOW

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    IMPORTANT SAFETY INFORMATION

    Before you take TYVASO, tell your healthcare provider about all of your medical conditions, including if you:

    • Have lung disease, such as asthma or chronic obstructive pulmonary disease (COPD)
    • Have a lung infection

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    IMPORTANT SAFETY INFORMATION

    Before you take TYVASO, tell your healthcare provider about all of your medical conditions, including if you:

    • Have lung disease, such as asthma or chronic obstructive pulmonary disease (COPD)
    • Have a lung infection
    • Have liver or kidney problems
    • Have low blood pressure
    • Have bleeding problems
    • Are pregnant or plan to become pregnant. It is not known if TYVASO will harm your unborn baby.
    • Are breast-feeding or plan to breast-feed. It is not known if TYVASO passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with TYVASO.

    Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. TYVASO and other medicines may affect each other.

    Especially tell your healthcare provider if you take:

    • Medicines used to treat high blood pressure or heart disease
    • Medicines that decrease blood clotting (anticoagulants)
    • Water pills (diuretics)
    • Gemfibrozil (Lopid) or rifampin (Rimactane, Rifadin, Rifamate, Rifater)
    What are the possible side effects of TYVASO?

    TYVASO can cause serious side effects, including:

    • Low blood pressure (symptomatic hypotension). If you have low blood pressure, TYVASO may lower your blood pressure more.
    • Bleeding problems. TYVASO may increase the risk of bleeding, especially in people who take blood thinners (anticoagulants).

    The most common side effects of TYVASO are cough, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), fainting or loss of consciousness, dizziness, and diarrhea. These are not all the possible side effects of TYVASO. Call your doctor for medical advice about side effects.

    You may report side effects to the FDA at

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    www.fda.gov/MedWatch
    or call 1-800-FDA-1088.

    What is TYVASO?

    TYVASO (treprostinil) is a prescription medicine used in adults to treat pulmonary arterial hypertension (PAH; WHO Group 1), which is high blood pressure in the arteries of your lungs. TYVASO can improve the ability to exercise. Your ability to exercise decreases 4 hours after taking TYVASO. It is not known if TYVASO is safe and effective in children under 18 years of age.

    The risk information provided here is not comprehensive. To learn more about TYVASO, talk with your healthcare provider. Please see Full Prescribing Information, Patient Product Information, and the TD-100 and TD-300 TYVASO® Inhalation System Instructions for Use manuals at www.tyvaso.com or call 1-877-UNITHER (1-877-864-8437).

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    WHO=World Health Organization.

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    use by US residents only.

    TYVASO is a registered trademark of United Therapeutics Corporation.

    All other brands are trademarks of their respective owners. The makers of these brands are not affiliated with United Therapeutics or its products.

    ©2020 United Therapeutics Corporation. All rights reserved. US-TYV-0414