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Find helpful information and videos and support for Tyvaso, a prescription medicine approved for adults with pulmonary arterial hypertension (PAH) (WHO Group 1).

About PAH


Affects your body

Pulmonary arterial hypertension is high blood pressure in the arteries of the lungs. This increased pressure affects the ability of the heart and lungs to work properly.
Here is how blood vessels, lungs, and heart function normally, compared with those affected by PAH.
The blood vessels in the lungs are wide enough so blood can flow through them freely.
The blood vessels in the lungs become narrow, making it difficult for blood to flow through them.
As the blood flows through the blood vessels in the lungs, it picks up the oxygen it needs to deliver to the rest of the body.
Because the blood vessels are too narrow, less blood is able to pass through the lungs and carry oxygen to the rest of the body.
The heart pumps normally to push blood through the blood vessels in the lungs.
The right ventricle of the heart has to pump harder to push blood through the lungs, causing the right side of the heart to become enlarged and the walls of the heart to thicken. This puts tremendous stress on the heart, weakening it over time, which can lead to right-heart failure.

An imbalance of

3 natural chemicals

leads to pah

Prostacyclin, endothelin, and nitric oxide are 3 substances that are naturally produced in the body. They all play a part in ensuring that blood can flow through the blood vessels freely. When the levels of these 3 substances become imbalanced, it can cause the blood vessels—specifically those in the lungs—to narrow, leading to PAH.
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Find out more about PAH on www.unitedpahsupport.com.

About us

Important Safety Information for Tyvaso

Before you take Tyvaso, tell your healthcare provider about all of your medical conditions, including if you:

  • Have lung disease, such as asthma or chronic obstructive pulmonary disease (COPD)
  • Have a lung infection
  • Have liver or kidney problems
  • Have low blood pressure
  • Have bleeding problems
  • Are pregnant or plan to become pregnant. It is not known if Tyvaso will harm your unborn baby.
  • Are breast-feeding or plan to breast-feed. It is not known if Tyvaso passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with Tyvaso.

Tell your healthcare provider about all the medicines you take , including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tyvaso and other medicines may affect each other.

Especially tell your healthcare provider if you take:

  • Medicines used to treat high blood pressure or heart disease
  • Medicines that decrease blood clotting (anticoagulants)
  • Water pills (diuretics)
  • Gemfibrozil (Lopid) or rifampin (Rimactane, Rifadin, Rifamate, Rifater)

What are the possible side effects of Tyvaso?

Tyvaso can cause serious side effects, including:

  • Low blood pressure (symptomatic hypotension). If you have low blood pressure, Tyvaso may lower your blood pressure more
  • Bleeding problems. Tyvaso may increase the risk of bleeding in people who take blood thinners (anticoagulants)

The most common side effects of Tyvaso are cough, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), fainting or loss of consciousness, dizziness, and diarrhea. These are not all the possible side effects of Tyvaso. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.

What is Tyvaso?

Tyvaso (treprostinil) is a prescription medicine used in adults to treat pulmonary arterial hypertension (PAH; WHO Group I), which is high blood pressure in the arteries of your lungs. Tyvaso can improve the ability to exercise. Your ability to exercise decreases 4 hours after taking Tyvaso. It is not known if Tyvaso is safe and effective in children under 18 years of age.


Please see the Full Prescribing Information, Patient Product Information, and the Tyvaso Inhalation System Instructions for Use manual.

For additional information about Tyvaso, visit www.tyvaso.com or call 1-877-UNITHER (1-877-864-8437).

This information is provided for an informational purpose and is not intended as treatment advice. Patients should consult a healthcare professional for treatment advice.

The information contained in this section of the site is clinical in nature and specifically created for healthcare professionals. If you are not a US healthcare professional, please click CLOSE to return to the consumer section of the site.
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