Approaches to Help Manage the Most Common Side Effects

It is NOT unusual to experience side effects when starting Tyvaso. If you do experience side effects, the first thing you should do is talk to your doctor or healthcare professional. They will want to first ensure that you are using the Tyvaso Inhalation System properly. Below are some additional tips that may help you if you experience some of the most common side effects associated with Tyvaso.

The following potential approaches to managing the most common side effects with Tyvaso are based on anecdotal evidence and should not be construed as medical advice. United Therapeutics does not recommend or endorse using healthcare products other than as directed or prescribed.

Talk to your doctor about strategies that may help manage the side effects you experience while on Tyvaso.

If you experience cough or throat irritation:

Before treatment:

During treatment:

After treatment:

Your doctor may also recommend lowering your dose (taking fewer breaths) until your cough goes away, so make sure you talk to your doctor.

If you experience nausea or diarrhea:

If you experience headaches:

Next: Important Information if You’ve Just Been Prescribed Tyvaso


Before you take Tyvaso, tell your healthcare provider about all of your medical conditions, including if you:

It is important to tell your healthcare provider about all the medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements, as they may affect your use of Tyvaso by increasing the risk of side effects or decreasing effectiveness. Especially tell your healthcare provider if you take any of these medicines:

The most common side effects of Tyvaso are coughing, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), and fainting or loss of consciousness. These are not all the possible side effects of Tyvaso. Tell your healthcare provider about any side effects that bother you or do not go away. Your healthcare provider may be able to help you manage the side effects.


Tyvaso is a prescription medicine used in adults to treat pulmonary arterial hypertension (PAH) (WHO Group 1), which is high blood pressure in the arteries of your lungs. Tyvaso can improve exercise ability in people who also take bosentan (an endothelin receptor antagonist, (ERA)) or sildenafil (a phosphodiesterase-5 (PDE-5) inhibitor). Your ability to do exercise decreases 4 hours after taking Tyvaso.

The effects of Tyvaso are unknown in patients under 18 years of age.


Please see the Full Prescribing Information, Patient Package Insert, and the Tyvaso Inhalation System Instructions for Use manual.

For additional information about Tyvaso, visit or call 1-877-UNITHER (1-877-864- 8437).

Call your healthcare provider for medical advice about side effects. You may report side effects to the FDA at or call 1-800-FDA-1088.

This information is provided for an informational purpose and is not intended as treatment advice. Patients should consult a healthcare professional for treatment advice.