Register
for UpdatesSend to a
Friend Text Size
A A A Print
Page

Important Safety Information Full Prescribing Information Patient Package Insert Instructions For Use

Learn More

Click Here

Learn More

How to Get Tyvaso

You need a prescription from your doctor to receive both Tyvaso^® and the Tyvaso Inhalation System.

Talk to your doctor about Tyvaso and get all of your questions answered. Only your doctor can help determine if Tyvaso is right for you. Make sure to let them know of any other medical conditions you have as well as other medicines you’re taking, or any vitamins, herbal supplements, or nonprescription drugs you are taking or would like to take. Tyvaso and other medications may affect each other. It’s especially important to:

• Tell your doctor if you have liver or kidney problems, as these may affect your ability to tolerate Tyvaso
• Ask your doctor whether or not you should take Tyvaso if you’re pregnant, planning to become pregnant, or are breast-feeding an infant
• Tell your doctor if you’re taking gemfibrozil (Lopid^®), a drug used to lower high blood cholesterol
• Tell your doctor if you’re taking rifampin (Rimactane^®, Rifadin^®, Rifamate^®, Rifater^®), an antibiotic used to treat infections

Tyvaso and the Tyvaso Inhalation System are only available through a Specialty Pharmacy Service (SPS) provider. Contact your SPS provider if you have any questions about taking Tyvaso, operating the Tyvaso Inhalation System, or if you need more medication.

Tell your doctor if your symptoms get worse or you experience side effects that won’t go away or are causing you distress.

Indication

Tyvaso is a prescription medicine used in adults to treat pulmonary arterial hypertension (PAH) (WHO Group 1), which is high blood pressure in the arteries of your lungs. Tyvaso can improve exercise ability in people who also take bosentan (an endothelin receptor antagonist) or sildenafil (a phosphodiesterase-5 inhibitor). The effects decrease over 4 hours; treatment timing can be adjusted for planned activities.

Studies establishing effectiveness included predominately patients with NYHA Functional Class III symptoms and etiologies of idiopathic or heritable PAH (56%) or PAH associated with connective tissue diseases (33%).

Important Safety Information for Tyvaso

• Tyvaso is breathed in (inhalable) through your mouth into your lungs. Tyvaso should only be used with the Tyvaso Inhalation System
• The effects of Tyvaso are unknown in patients with lung disease (such as asthma or chronic obstructive pulmonary disease) and in patients under 18 years of age
• If you have low blood pressure, Tyvaso may cause symptomatic hypotension (low blood pressure)
• Because Tyvaso reduces the ability of your blood to clot (coagulate), it may increase your risk for bleeding if you are taking blood thinners (anticoagulants), such as warfarin or heparin
• The use of Tyvaso with diuretics (water pills), antihypertensives (medications used to treat high blood pressure or heart disease), or other vasodilators (medications that lower blood pressure) may increase your risk for hypotension (low blood pressure)

Other medical conditions and medicines may affect your use of Tyvaso by increasing the risk of side effects or decreasing effectiveness. It is important to tell your doctor about your medical conditions and any medicines you may be taking, including:

• If you are taking gemfibrozil (for high cholesterol) or rifampin (for infection), your Tyvaso dosage may need adjustment
• If you have liver or kidney problems, your ability to tolerate Tyvaso may be affected
• If you are pregnant, breast-feeding, or planning to become pregnant, talk with your healthcare provider about whether you should take Tyvaso

The most common side effects of Tyvaso are coughing, headache, throat irritation and pain, nausea, reddening of the face and neck (flushing), and fainting or loss of consciousness. These are not all the possible side effects of Tyvaso. Tell your doctor about any side effects that bother you or do not go away. Your doctor may be able to help you manage the side effects.

For more information about Tyvaso, please see the Full Prescribing Information, Patient Package Insert, and the Tyvaso Inhalation System Instructions for Use Manual. Questions? Call the Customer Service Line at 1-877-UNITHER (1-877-864-8437).

Tyvaso FAQs|Important Safety Information|Full Prescribing Information|Patient Package Insert|Instructions for Use Manual

Site Map|Contact Us|Privacy Policy|Terms of Use|About United Therapeutics

©2013 United Therapeutics Corporation. All rights reserved. US/TYV/OCT12/169
Tyvaso is a registered trademark of United Therapeutics Corporation. All other trademarks and registered trademarks are the property of their respective owners.
This site is intended for use by U.S. residents only.